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Did you know?

Patients on Plaquenil need ongoing retinal monitoring

Retinal toxicity can occur before symptoms ever develop — which is exactly why screening can’t wait for a complaint. EyeSee makes that monitoring simple to do in-house.

Prescription medication — patients on hydroxychloroquine need retinal monitoring.

Early detection today.

A single retinal image screens for hydroxychloroquine toxicity — read by an ophthalmologist, not an algorithm alone.

  • Toxicity is often silent

    Damage can progress before a patient notices any change in vision.

  • And it’s irreversible

    Once retinal damage occurs it can’t be undone — so early detection is everything.

  • Your camera, your patient

    RetinaVue-compatible and device-agnostic. No referral out the door.

The patient population

Who takes hydroxychloroquine — and why it matters to you

Plaquenil (hydroxychloroquine) treats rheumatoid arthritis, lupus, and other autoimmune disorders. These patients often take it for years, and they’re already being seen — in rheumatology, primary care, and on-site clinics. That’s your opportunity to screen them where they already are.

Rheumatoid Arthritis

A cornerstone DMARD for RA, often taken for years to control joint inflammation — exactly the long-term exposure that raises retinal-toxicity risk.

Systemic Lupus (SLE)

Hydroxychloroquine is foundational therapy for lupus. Many patients stay on it indefinitely, making ongoing retinal surveillance essential.

Other Autoimmune Disorders

Sjögren’s, mixed connective-tissue disease, and other inflammatory conditions are also managed with hydroxychloroquine — and carry the same monitoring need.

Hands of an older adult — autoimmune conditions are treated with Plaquenil.
Photo: Towfiqu barbhuiya
The clinical case

Why annual retinal screening matters

Hydroxychloroquine retinal toxicity is the kind of complication that gives no early warning — which is exactly why a structured screening program exists. Here’s the reasoning in plain terms.

It can appear before symptoms

Retinal changes from hydroxychloroquine can develop while a patient still sees perfectly well. By the time vision is affected, damage may already be done.

And it’s irreversible

There is no treatment to reverse established toxicity. The only protective tool is catching changes early — and that requires looking, not waiting.

Guidelines call for monitoring

General ophthalmology guidance recommends a baseline retinal evaluation within the first year, then regular annual screening — with closer attention after roughly five years of use or with added risk factors.

EyeSee provides the remote interpretation; the prescribing physician sets the clinical schedule and any dosing decisions. We keep guidance general — your patient’s rheumatologist or primary physician owns the care plan.

24–48 hr
Report turnaround

From upload to physician report

5+ yrs
When risk climbs

Cumulative use raises toxicity risk

100%
Board-certified reads

Every image, a licensed ophthalmologist

0
Referrals out the door

The patient stays in your practice

The workflow

A RetinaVue-compatible screening workflow

Screening a Plaquenil patient is the same four-step flow you’d use for diabetic eye disease — capture in-house, upload, an ophthalmologist reads it for signs of hydroxychloroquine toxicity, and a report comes back in 24–48 hours.

  1. 1

    Capture

    Patient photo

    Your staff captures the retinal image during a routine visit using your existing fundus camera — RetinaVue, Optomed, Topcon, and most platforms supported.

  2. 2

    Upload

    Securely send

    One click sends the image to EyeSee through your camera portal or our secure, HIPAA-aligned upload — no new software or workflow disruption.

  3. 3

    Ophthalmologist Review

    Expert interpretation

    A board-certified ophthalmologist reviews the image, documents findings, and writes clinical impressions and recommendations.

  4. 4

    Report Returned

    24–48 hours

    You receive a clear, structured report — ready for the chart and the conversation with your patient — typically within 24–48 hours.

The interpretation

The EyeSee read & report

Every image is interpreted by a board-certified ophthalmologist — never an algorithm alone. Here’s what the physician evaluates and what comes back to your chart.

Macular & fundus assessment

A board-certified ophthalmologist reviews the macula and surrounding retina for early signs consistent with hydroxychloroquine toxicity.

Clear clinical impression

Plain-language findings — normal, monitor, or refer — documented and ready to drop straight into the chart.

Actionable recommendations

Guidance on follow-up interval and whether the case warrants a discussion with the prescribing rheumatologist.

24–48 hour turnaround

Reports return before the patient’s next visit, so the conversation about their medication can happen without delay.

Physician reading a clinical report on a laptop.
Photo: cottonbro studio
HCQ screening — read
29 hrs

No signs of hydroxychloroquine toxicity. Continue annual monitoring.

One question, every visit

Don’t forget to ask:

“Are you currently taking Plaquenil?”

It’s the simplest way to catch a patient who’s due for monitoring. If the answer is yes, a retinal image during today’s visit closes the gap — no separate appointment, no referral out the door.

Questions, answered

Plaquenil monitoring — common questions

Why does Plaquenil (hydroxychloroquine) require retinal monitoring?
Hydroxychloroquine — used for rheumatoid arthritis, lupus, and other autoimmune disorders — can cause retinal toxicity before symptoms develop. Guidelines call for a baseline exam and regular monitoring, and retinal imaging makes that easy to do in-house.
When should baseline and follow-up screening happen?
General ophthalmology guidance recommends a baseline retinal evaluation within the first year of starting hydroxychloroquine, then ongoing annual screening — with closer monitoring after about five years of use or when additional risk factors are present. EyeSee provides the interpretation; your patient’s prescribing physician sets the clinical schedule.
Can we do Plaquenil monitoring in our own clinic?
Yes — that’s the whole point. Your staff captures a retinal image during a routine visit with your existing fundus camera, uploads it, and a board-certified ophthalmologist interprets it for signs of hydroxychloroquine toxicity. The patient never has to be referred out for separate screening.
Does EyeSee prescribe or adjust the medication?
No. EyeSee is a remote reading service — think radiology, but for eyes. We interpret the retinal image and return findings and recommendations. Dosing and medication decisions remain with the prescribing rheumatologist or physician.
What camera do we need for Plaquenil screening?
We’re device-agnostic. The workflow is RetinaVue-compatible and also works with Optomed, Topcon, Canon, ZEISS, and most fundus platforms. If you already image patients for diabetic eye disease, you can screen Plaquenil patients with the same equipment.
Add Plaquenil monitoring

Screen your Plaquenil patients without sending them out

Stand up hydroxychloroquine retinal monitoring with the camera you already own. Board-certified reads, reports in 24–48 hours, and the patient stays yours.